EXCELLENT COMBINATION OF THESE TWO DRUGS TO FIGHT FIBROMYALGIA PAIN

A Canadian researcher think he has uncovered one. Ian Gilron is the Director of Clinical Pain Research, Professor of Anesthesiology, and Biomedical Sciences, and Faculty in the Centre for Neuroscience Studies at Queen’s University in Kingston, Ontario, Canada

The results of a trial suggest that combining pregabalin (Lyrica), an anti-seizure drug, with duloxetine (Cymbalta), an antidepressant, can safely improve outcomes in fibromyalgia, including not only pain relief, but also physical function and overall quality of life. Until now, these drugs have been proven, individually, to treat fibromyalgia pain.
“Previous evidence supports added benefits with some drug combinations in fibromyalgia,” says, Dr. Gilron. “We are very excited to present the first evidence demonstrating superiority of a duloxetine-pregabalin combination over either drug alone.”

Fibromyalgia was initially thought to be a musculoskeletal disorder. Research now suggests it’s a disorder of the central nervous system – the brain and spinal cord. Researchers believe that fibromyalgia amplifies painful sensations by affecting the level and activity of brain chemicals responsible for processing pain signals.

“The condition affects about 1.5 to 5 per cent of Canadians – more than twice as many women as men. It can have a devastating on the lives of patients and their families,” explains Dr. Gilron. “Current treatments for fibromyalgia are either ineffective or intolerable for many patients.”

This study is the latest in a series of clinical trials – funded by the Canadian Institutes of Health Research (CIHR) – that Dr. Gilron and his colleagues have conducted on combination therapies for chronic pain conditions. By identifying and studying promising drug combinations, their research is showing how physicians can make the best use of current treatments available to patients.

“The value of such combination approaches is they typically involve drugs that have been extensively studied and are well known to health-care providers,” says Dr. Gilron.

This new research was published in the journal Pain.

Dr. Gilron and his research team at Queen’s are members of the SPOR Network on Chronic Pain. The national network, funded under Canada’s Strategy for Patient-Oriented Research, directs new research, trains researchers and clinicians, increases access to care for chronic pain sufferers, and speeds up the translation of the most recent research into practice.

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5 Responses

  1. Alan says:

    What a crock of manure this article peddles.
    How much did the pharmaceutical billion industry paid you to write such trash?
    The amount of people suffering from fibromayalgia while on these drugs AND other extreme side effects is infernal yet you’re ainging praises to your sponsors.

  2. Nadine says:

    The duloxetine does help me, with gabapentin, baclofen, and a strong narcotic. But the Lyrica only made fibro worse for me.

  3. Melissa n says:

    Lyrics made me worse!

  4. Grace says:

    This statement is the only one I can agree with. 40 years of attempting to discover the many triggers and how to prevent them including prescription drugs, natural remedies, and still the flare ups are illusive. neurologist told me at the onset of symptoms that my brain sends wrong messages to my body and it would take him too long to figure out why. Remedies that have a positive effect may last up to 3 months and then the story changes…..Sincere compassion for my fellow fibro experiencers.
    Fibromyalgia was initially thought to be a musculoskeletal disorder. Research now suggests it’s a disorder of the central nervous system – the brain and spinal cord. Researchers believe that fibromyalgia amplifies painful sensations by affecting the level and activity of brain chemicals responsible for processing pain signals.

  5. eileen zacconi says:

    Two very dirty drugs with lots of side effects and withdrawal issues – makes sense to me, LOL. Also, many states are putting gabapentin on their controlled drug list due to it being abused. I wonder who was paying the author.

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